Nanjing Kershine Biotechnology Co.,Ltd

Fermentation Process

Optimize fermentation parameters based on yeast characteristics, refine strain selection, and implement appropriate fermentation strategies to ensure the quality of the raw materials.

Extraction technology

A patented enzymatic hydrolysis process is employed to achieve complete water solubility of yeast β-glucan, with no organic solvent residues, preservation of bioactivity, removal of most impurities, and reduced downstream purification burden.

Purity Control

A multi-stage purification process is employed to remove trace impurities, coupled with precise analytical monitoring to ensure purity, while simultaneously preserving the β-1,3/1,6 active structure and guaranteeing that both product purity and biological activity meet stringent standards.

Stability Technology

Optimize packaging and storage conditions to inhibit degradation and oxidation; conduct stability studies to maintain the activity and physicochemical properties of yeast β-glucan, thereby extending product shelf life and ensuring consistent performance in applications.

R&D Team

The company has assembled a team of experts in biofermentation, enzyme engineering, and separation and purification, with a deep focus on the R&D and industrialization of yeast polysaccharides. It has independently developed patented enzymatic hydrolysis technology, concentrating on strain optimization and the protection of the β-1,3/1,6 active structure, thereby establishing robust core technological barriers for its products.

Laboratory equipment

Equipped with high-precision R&D and testing instruments, we conduct comprehensive, end-to-end testing and analysis. Utilizing advanced techniques such as high-performance liquid chromatography and mass spectrometry, we rigorously control enzymatic hydrolysis efficiency and product purity, ensuring zero residual organic solvents and intact bioactive structures, thereby providing robust data support for process and quality stability.

Production Workshop

We employ standardized cleanroom facilities and adhere to stringent quality standards to achieve fully automated, closed-loop production across the entire process, rigorously controlling microbial and impurity risks. Leveraging large-scale production capacity and meticulous management, we ensure batch-to-batch consistency and uniform product quality, thereby meeting the raw-material supply needs of multiple industries.

End-to-end quality control

A comprehensive, end-to-end quality control system has been established, covering raw material receipt, fermentation, enzymatic hydrolysis, extraction, and finished-product shipment. Multiple inspections are conducted at critical process steps, with real-time recording of process and quality parameters, ensuring controllable production, traceable issues, and preventable risks, thereby guaranteeing a stable supply of high-quality yeast β-glucan raw materials.

Third-party testing

Key performance indicators are entrusted to authoritative third-party independent testing, covering parameters such as ingredient content, structural identification, solvent residues, microbiological testing, and heavy metals, to provide objective reports that substantiate product quality, ensure application safety, and enhance customer trust.

Traceability System

Establish a full-process traceability system that leverages batch coding to enable end-to-end tracking of strain origins, production processes, quality testing, and finished-product distribution, thereby complying with regulatory requirements across the food, cosmetics, and pharmaceutical industries and ensuring product transparency and consumer confidence.