Professional production of yeast β-glucan


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About us

Nanjing Kershine Biotechnology Co.,Ltd

Nanjing Kershine Biotechnology Co.,Ltd. was established in 2024. Leveraging the years of technological expertise accumulated by its affiliated companies and integrating core R&D and production capabilities, the company operates a 3,500-square-meter independent R&D and manufacturing facility. It is a high-tech enterprise dedicated to the in-depth development of yeast β-glucan.

The company has established deep expertise in the yeast-derived carbohydrate bioactive ingredients sector, holding numerous national invention patents and obtaining a wide array of internationally recognized certifications, including U.S. FDA registration for food facilities, Halal certification, EU and China new-food-source approvals, and ISO four-system integrations.

16 year

16 years of focus on raw materials

3500

Factory area: 3,500 square meters

SGS/CPSR/Halal Certification

Multiple patents

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Nanjing Kershine Biotechnology Co.,Ltd
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OUR PRODUCTS

Pioneering dextran innovation and defining a natural, trustworthy biofuture.

Yeast β-Glucan Freeze-Dried Powder

Yeast β-Glucan Freeze-Dried Powder

Number: K90

Purity: 98%

Specifications: 1 kg/bag, 5 kg/box, 10 kg/box

Applicable to: High-concentration efficacy, face cream, ampoule, and freeze-dried powder formulations

Yeast β-Glucan Aqueous Solution

Yeast β-Glucan Aqueous Solution

Number: KS910

Purity: 10%

Specifications: 1 kg/bag, 10 kg/bag, 25 kg/drum

Applicable to: Effective serums, salon-grade masks, and high-performance products

Yeast β-Glucan Aqueous Solution

Yeast β-Glucan Aqueous Solution

Number: KS901

Purity: 1%

Specifications: 1 kg/bag, 10 kg/bag, 25 kg/drum

Applicable to: Water, spray, facial mask, ordinary gel

Purity Can Be Customized According To Requirements.

If you are interested in our products, please fill out the relevant information and submit it; a member of our staff will contact you promptly. Alternatively, feel free to call us directly.

Custom Message

Application Fields

Harnessing Nature’s Pure Essence, Redefining Luxury Living with Cutting-Edge Technology

Cosmetic grade

Key benefits: barrier repair, soothing and stabilization, strengthening the skin’s foundation, anti-irritation, and moisturization.

Applicable Products:

Repairing serum, ampoule, and skin primer

Soothing toner, mist, and essence water

Repairing mask, sleeping mask, mask serum

Sensitive Skin Creams, Lotions, and Gels

Medical cold compress patches, postoperative repair dressings, gel

Sunscreen, base makeup, and other gentle, skin-nourishing cosmetics

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Cosmetics

Pharmaceutical grade

Key benefits: immune modulation, mucosal repair, anti-inflammatory soothing, and supportive healing.

Applicable Products:

Oral care: oral ulcer gel, mouthwash, and lozenges

Topical skin applications: auxiliary repair ointments and creams for eczema and dermatitis

Wound Care: Wound Repair Gel, Dressings

Gut Health: Intestinal Mucosal Repair Preparations

Immune-modulating health foods / pharmaceutical raw materials

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Medicine

Food-grade

Key benefits: immune regulation, gut health, antioxidant protection, and enhanced immunity.

Applicable Products:

Functional solid beverages, protein powders, and nutritional instant mixes

Probiotic-Combined Health Supplements

Dairy products, yogurt, and formulated milk powder

Candies, compressed candies, gummies

Immune-Boosting Formula Foods for Infants and Young Children / Middle-Aged and Older Adults

Sports nutrition, meal replacements, and healthy snacks

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Food

Why Choose Us?

Precision, Global Reach, and Artisan Craftsmanship: The Premier Choice for Premium Ingredients

Fermentation Process

Optimize fermentation parameters based on yeast characteristics, refine strain selection, and implement appropriate fermentation strategies to ensure the quality of the raw materials.

Extraction technology

A patented enzymatic hydrolysis process is employed to achieve complete water solubility of yeast β-glucan, with no organic solvent residues, preservation of bioactivity, removal of most impurities, and reduced downstream purification burden.

Purity Control

A multi-stage purification process is employed to remove trace impurities, coupled with precise analytical monitoring to ensure purity, while simultaneously preserving the β-1,3/1,6 active structure and guaranteeing that both product purity and biological activity meet stringent standards.

Stability Technology

Optimize packaging and storage conditions to inhibit degradation and oxidation; conduct stability studies to maintain the activity and physicochemical properties of yeast β-glucan, thereby extending product shelf life and ensuring consistent performance in applications.

R&D Team

The company has assembled a team of experts in biofermentation, enzyme engineering, and separation and purification, with a deep focus on the R&D and industrialization of yeast polysaccharides. It has independently developed patented enzymatic hydrolysis technology, concentrating on strain optimization and the protection of the β-1,3/1,6 active structure, thereby establishing robust core technological barriers for its products.

Laboratory equipment

Equipped with high-precision R&D and testing instruments, we conduct comprehensive, end-to-end testing and analysis. Utilizing advanced techniques such as high-performance liquid chromatography and mass spectrometry, we rigorously control enzymatic hydrolysis efficiency and product purity, ensuring zero residual organic solvents and intact bioactive structures, thereby providing robust data support for process and quality stability.

Production Workshop

We employ standardized cleanroom facilities and adhere to stringent quality standards to achieve fully automated, closed-loop production across the entire process, rigorously controlling microbial and impurity risks. Leveraging large-scale production capacity and meticulous management, we ensure batch-to-batch consistency and uniform product quality, thereby meeting the raw-material supply needs of multiple industries.

End-to-end quality control

A comprehensive, end-to-end quality control system has been established, covering raw material receipt, fermentation, enzymatic hydrolysis, extraction, and finished-product shipment. Multiple inspections are conducted at critical process steps, with real-time recording of process and quality parameters, ensuring controllable production, traceable issues, and preventable risks, thereby guaranteeing a stable supply of high-quality yeast β-glucan raw materials.

Third-party testing

Key performance indicators are entrusted to authoritative third-party independent testing, covering parameters such as ingredient content, structural identification, solvent residues, microbiological testing, and heavy metals, to provide objective reports that substantiate product quality, ensure application safety, and enhance customer trust.

Traceability System

Establish a full-process traceability system that leverages batch coding to enable end-to-end tracking of strain origins, production processes, quality testing, and finished-product distribution, thereby complying with regulatory requirements across the food, cosmetics, and pharmaceutical industries and ensuring product transparency and consumer confidence.

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Keshang | Official Invitation to the 30th CBE China Beauty Expo

Keshang | Official Invitation to the 30th CBE China Beauty Expo

The 30th CBE China Beauty Expo will be grandly held from May 12 to 14, 2026, at the Shanghai New International Expo Center, bringing together over 3,500 global companies and showcasing more than 80,000 new products and technological innovations. It is an unmissable annual flagship event for the beauty industry value chain.

How can the stability of yeast β-glucan aqueous solutions be improved?

Time:2026-03-06

Aqueous solutions of yeast β‑glucan are most stable in the pH range of 4.0–8.0. Excessive acidity or alkalinity can lead to turbidity, precipitation, or reduced activity. During production, adjusting the system pH to a neutral to slightly alkaline level can significantly enhance stability.

What is the stability of yeast β-glucan aqueous solutions?

Time:2026-03-06

Aqueous solutions of yeast β‑glucan exhibit excellent overall stability and can be stored for 6 to 12 months under ambient temperature, in the dark, and in sealed conditions without layering, precipitation, or significant degradation.

“Active Freshness-Locking” Process for Freeze-Dried Yeast β-Glucan Powder

Time:2026-03-06

Yeast β-glucan lyophilized powder is produced using low-temperature vacuum freeze-drying, which rapidly dehydrates the material at –40°C to –60°C, thereby fully preserving the bioactive triple-helix structure of β-1,3/1,6 highly branched glucans.

Key Differences Between Freeze-Dried Powder and Ordinary Powder

Time:2026-03-06

Conventional yeast β-glucan is typically produced via spray drying, which can easily damage its structure, resulting in poor solubility and a tendency to cake; in contrast, freeze-dried powder avoids high-temperature degradation, maintaining structural integrity and higher biological activity, while exhibiting excellent rehydration properties and more uniform dissolution.

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