“Active Freshness-Locking” Process for Freeze-Dried Yeast β-Glucan Powder


Yeast β-glucan lyophilized powder is produced using low-temperature vacuum freeze-drying, which rapidly dehydrates the material at –40°C to –60°C, thereby fully preserving the bioactive triple-helix structure of β-1,3/1,6 highly branched glucans. The product boasts a purity of 85%–95% and a moisture content of ≤3%, and can be stably stored for 24 months under cool, dry conditions at room temperature. Compared with conventional drying methods, freeze-drying increases the retention rate of bioactivity by more than 30%, making it an ideal raw material for health supplements and high-end skincare products.

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How can the stability of yeast β-glucan aqueous solutions be improved?

Aqueous solutions of yeast β‑glucan are most stable in the pH range of 4.0–8.0. Excessive acidity or alkalinity can lead to turbidity, precipitation, or reduced activity. During production, adjusting the system pH to a neutral to slightly alkaline level can significantly enhance stability.


What is the stability of yeast β-glucan aqueous solutions?

Aqueous solutions of yeast β‑glucan exhibit excellent overall stability and can be stored for 6 to 12 months under ambient temperature, in the dark, and in sealed conditions without layering, precipitation, or significant degradation.


“Active Freshness-Locking” Process for Freeze-Dried Yeast β-Glucan Powder

Yeast β-glucan lyophilized powder is produced using low-temperature vacuum freeze-drying, which rapidly dehydrates the material at –40°C to –60°C, thereby fully preserving the bioactive triple-helix structure of β-1,3/1,6 highly branched glucans.


Key Differences Between Freeze-Dried Powder and Ordinary Powder

Conventional yeast β-glucan is typically produced via spray drying, which can easily damage its structure, resulting in poor solubility and a tendency to cake; in contrast, freeze-dried powder avoids high-temperature degradation, maintaining structural integrity and higher biological activity, while exhibiting excellent rehydration properties and more uniform dissolution.